Human fat cell beta-adrenergic receptors: beta-agonist-dependent lipolytic responses and characterization of beta-adrenergic binding sites on human fat cell membranes with highly selective beta 1-antagonists.
نویسندگان
چکیده
منابع مشابه
Beta-Adrenergic Receptors and Fat Loss
HISTORY OF MESOTHERAPY This review of basic pharmacology using ephedrine as an active medication is provided by Bryan Haycock, MS, CSCS, founder of HSN. As a sympathomimetic, ephedrine acts to stimulate the sympathetic nervous system. It does this by causing presynaptic nerve terminals to release norepinephrine, or what is commonly called noradrenaline (NA), into the synaptic space. It also has...
متن کاملBeta-Adrenergic Receptors
ion fluxes in these cells, we have now examined the possibility that the decrease in beta receptor number might be associated with concomitant changes in catecholamine-dependent potassium ion transport. Hypothyroid turkey erythrocytes display decreased sensitivity to isoproterenol-stimulated potassium influx. Half-maximal stimulation of potassium influx occurs at 9.2±+1.7 nM in hypothyroid cell...
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[3F1] Propnamioolool 1)iti(ii5 roopidly tiIi(h nO’vensil)lV to sites in mii(’miih)m’aIiO’s l)l’o’l)mir(’d fronts ‘atiiite vo-’mitnietolar Iti\’oocardiumil. ‘j’\\ j oot’do’rs oof sito’s wero’ identified. Tho’ htighto’r-order sito’s have a vmtluo’ (o’luilillniuni coonstmitit ) oof 4.57 X 10 ii-tm and a bimudimog cm-opacity of 3.2 X 10-s miioole/ trig oof’ Jlrooto’imo. 1’or thoo’ loowo’r-oordo’r s...
متن کاملBeta adrenergic receptors on cultured human retinal pigment epithelium.
Cultured fetal human retinal pigment epithelium (RPE) was grown on a permeable substrate and sealed in an Ussing chamber. The average electrical resistance (R) was 330 ohm-cm2, the average transepithelial voltage (Ve) was 3.0 mV (apical side positive), and the average short circuit current (Isc) was 9.1 microA/cm2. When these RPE preparations were exposed to isoproterenol (a beta-adrenergic ago...
متن کاملAn assay for beta-adrenergic receptors in isolated human fat cells.
The beta-adrenergic receptors have been characterized in isolated human adipocytes using a potent beta-adrenergic antagonist (-)-[3H]dihydroalprenolol. Binding of (-)-[3H]dihydroalprenolol to isolated fat cells was stereospecific and saturable, the maximum number of binding sites calculated being 7.8 +/- 2.2 pmol of bound ligand/10(7) cells, corresponding to 450,000 binding sites/cell. The diss...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 1988
ISSN: 0022-2275
DOI: 10.1016/s0022-2275(20)38502-3